Diagnostic Value of Immunohistochemical Staining of GP73, GPC3, DCP, CD34, CD31, and Reticulin Staining in Hepatocellular Carcinoma
نویسندگان
چکیده
منابع مشابه
Unusual reticulin staining pattern in well-differentiated hepatocellular carcinoma
BACKGROUND Special stains, such as reticulin stain and CD34 immunostain, are very helpful in the diagnosis of well differentiated hepatocellular carcinoma (HCC). Most studies have shown that absent or decreased reticulin stain or an abnormal reticulin pattern with widened trabeculae is reliable for the diagnosis of well-differentiated HCC. CASE REPORT We report here two cases of well differen...
متن کاملValidation of the endothelial staining markers CD31 and CD34 in immunohistochemistry of the long saphenous vein.
Background/Introduction Endothelial injury during the surgical intervention can significantly affect the functional status of the vein. The endothelial layer plays a vital role in the long saphenous vein for ensuring smooth blood flow and the prevention of vasoconstriction and thrombi formation within the blood vessels. There are few histological studies comparing the different vein harvesting ...
متن کاملDiagnostic utility of p63/P501S double sequential immunohistochemical staining in differentiating urothelial carcinoma from prostate carcinoma
BACKGROUND Distinguishing urothelial carcinoma (UC) from prostate carcinoma (PC) is important due to potential therapeutic and prognostic implications. However, this can be a diagnostic challenge when there is limited tissue and in poorly differentiated tumors. We evaluated the diagnostic utility of a dual immunohistochemical stain comprising p63 and P501S (prostein), applied sequentially on a ...
متن کاملThe Expression of P53 in Leukoplakia, Squamous Cell Carcinoma and Normal Oral Epithelium Using Immunohistochemical Staining Method
Background & Aims: Leukoplakia is the most common premalignant or potentially malignant lesion of the oral mucosa and its potentiality for malignant transformation is unpredictable. The aim of the present study was to evaluate p53 expression in normal oral epithelium, leukoplakia and oral squamous cell carcinoma. Methods: The standard Biotin streptavaidin peroxidase immunohistochemical staining...
متن کاملDiagnostic value of SOX-10 immunohistochemical staining for the detection of uveal melanoma
OBJECTIVES SOX-10 has been shown to be a sensitive marker of cutaneous melanoma. This study aimed to evaluate Sox-10 expression in uveal melanoma. METHODS A total of 40 tissue blocks of enucleated eyes with uveal melanoma were cut and stained using an anti-SOX-10 mouse monoclonal antibody and HMB-45 antibody. RESULTS SOX-10 showed exclusive nuclear positivity in 100% of the uveal melanoma c...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Histochemistry & Cytochemistry
سال: 2013
ISSN: 0022-1554,1551-5044
DOI: 10.1369/0022155413492771